Yong-hui Jiang Department of Genetics Yale University School of Medicine Biography Publications Institution JoVE Articles Yong-hui Jiang has not added a biography. If you are Yong-hui Jiang and would like to personalize this page please email our Author Liaison for assistance. Publications Impaired Synaptic Function and Hyperexcitability of the Pyramidal Neurons in the Prefrontal Cortex of Autism-associated Shank3 Mutant Dogs Molecular Autism. Jan, 2024 | Pubmed ID: 38297387 Critical Windows of Greenness Exposure During Preconception and Gestational Periods in Association with Birthweight Outcomes Environmental Research, Health : ERH. Mar, 2024 | Pubmed ID: 38022394 Identifying Critical Windows of Air Pollution Exposure During Preconception and Gestational Period on Birthweight: a Prospective Cohort Study Environmental Health : a Global Access Science Source. Oct, 2023 | Pubmed ID: 37858139 Modeling SHANK3-associated Autism Spectrum Disorder in Beagle Dogs Via CRISPR/Cas9 Gene Editing Molecular Psychiatry. Sep, 2023 | Pubmed ID: 37848710 Novel Epigenetic Molecular Therapies for Imprinting Disorders Molecular Psychiatry. Aug, 2023 | Pubmed ID: 37626134 Shank3 Deficits in the Anteromedial Bed Nucleus of the Stria Terminalis Trigger an Anxiety Phenotype in Mice The European Journal of Neuroscience. Jun, 2023 | Pubmed ID: 37165567 Estimation on Risk of Spontaneous Abortions by Genomic Disorders from a Meta-analysis of Microarray Results on Large Case Series of Pregnancy Losses Molecular Genetics & Genomic Medicine. Aug, 2023 | Pubmed ID: 37013615 CHD8 Mutations Increase Gliogenesis to Enlarge Brain Size in the Nonhuman Primate Cell Discovery. Mar, 2023 | Pubmed ID: 36878905 SHANK3 in Vagal Sensory Neurons Regulates Body Temperature, Systemic Inflammation, and Sepsis Frontiers in Immunology. 2023 | Pubmed ID: 36845137 Vitamin C Epigenetically Controls Osteogenesis and Bone Mineralization Nature Communications. Oct, 2022 | Pubmed ID: 36202795 A Retrospective Cohort Analysis of the Yale Pediatric Genomics Discovery Program American Journal of Medical Genetics. Part A. Oct, 2022 | Pubmed ID: 35899841 Comparative Proteome and Cis-Regulatory Element Analysis Reveals Specific Molecular Pathways Conserved in Dog and Human Brains Molecular & Cellular Proteomics : MCP. Aug, 2022 | Pubmed ID: 35738554 Recommendations for the Diagnosis and Management of Childhood Prader-Willi Syndrome in China Orphanet Journal of Rare Diseases. 06, 2022 | Pubmed ID: 35698200 Neural Circuit Pathology Driven by Shank3 Mutation Disrupts Social Behaviors Cell Reports. Jun, 2022 | Pubmed ID: 35675770 Detecting Regions of Homozygosity Improves the Diagnosis of Pathogenic Variants and Uniparental Disomy in Pediatric Patients American Journal of Medical Genetics. Part A. Jun, 2022 | Pubmed ID: 35199448 Inhibition of Trpv4 Rescues Circuit and Social Deficits Unmasked by Acute Inflammatory Response in a Shank3 Mouse Model of Autism Molecular Psychiatry. Apr, 2022 | Pubmed ID: 35022531 Mutations of the Histone Linker H1-4 in Neurodevelopmental Disorders and Functional Characterization of Neurons Expressing C-terminus Frameshift Mutant H1.4 Human Molecular Genetics. May, 2022 | Pubmed ID: 34788807 D-bifunctional Protein Deficiency Caused by Splicing Variants in a Neonate with Severe Peroxisomal Dysfunction and Persistent Hypoglycemia American Journal of Medical Genetics. Part A. Jan, 2022 | Pubmed ID: 34623748 Psychometric Properties of the Chinese Parent Version of the Autism Spectrum Rating Scale: Rasch Analysis Autism : the International Journal of Research and Practice. 10, 2021 | Pubmed ID: 33845648 Altered Striatum Centered Brain Structures in SHANK3 Deficient Chinese Children with Genotype and Phenotype Profiling Progress in Neurobiology. May, 2021 | Pubmed ID: 33388374 High Genetic Burden in 163 Chinese Children with Status Epilepticus Seizure. Jan, 2021 | Pubmed ID: 33278787 A Novel Chd8 Mutant Mouse Displays Altered Ultrasonic Vocalizations and Enhanced Motor Coordination Autism Research : Official Journal of the International Society for Autism Research. Oct, 2020 | Pubmed ID: 32815320 Intrathecal Injection – An Efficient and Reliable Delivery Method to Test the Efficacy of Gene Editing in Neonatal Mouse Brains Xiaona Lu1, Yong-hui Jiang1,2,3 1Department of Genetics, Yale University School of Medicine, 2Department of Neuroscience, Yale University School of Medicine, 3Department of Pediatrics, Yale University School of Medicine JoVE 65761 Neuroscience
Intrathecal Injection – An Efficient and Reliable Delivery Method to Test the Efficacy of Gene Editing in Neonatal Mouse Brains Xiaona Lu1, Yong-hui Jiang1,2,3 1Department of Genetics, Yale University School of Medicine, 2Department of Neuroscience, Yale University School of Medicine, 3Department of Pediatrics, Yale University School of Medicine JoVE 65761 Neuroscience