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Journal / Genetics / The Serial Anesthesia Array for the…
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Genetics

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JoVE Journal Genetics
The Serial Anesthesia Array for the High-Throughput Investigation of Volatile Agents Using Drosophila melanogaster
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The Serial Anesthesia Array for the High-Throughput Investigation of Volatile Agents Using Drosophila melanogaster

Article DOI: 10.3791/65144-v • 06:27 min • February 24th, 2023
February 24th, 2023 •
1, 1, 2, 1
1Department of Anesthesiology, University of Wisconsin-Madison, 2Department of Medical Genetics, University of Wisconsin-Madison

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Il moscerino della frutta (Drosophila melanogaster) è ampiamente utilizzato per la ricerca biologica e tossicologica. Per espandere l'utilità delle mosche, abbiamo sviluppato uno strumento, l'array di anestesia seriale, che espone simultaneamente più campioni di mosca agli anestetici generali volatili (VGA), rendendo possibile studiare gli effetti collaterali (tossici e protettivi) dei VGA.

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